Shadowrun: Lockdown - The player is one of the roughly hundred thousand folks trapped in the Renraku Arcology when it's central AI decides to lockdown and start playing god. I'd design it as an RPG/survival horror game, with the player creating their character and playing an intro mission befitting their class that explains why they're in the Arcology, then jumping ahead to them waking up in one of the hundreds of labs that the AI has set up to do experiments on the trapped populace.
To follow up on your idea with a slight tangent, how would you handle character advancement. I'm assuming by your description of the scenario and the survival horror moniker that game time would elapse in more or less real time and the total game world time that would elapse over the course of the game would be at most a few days. In such a situation how would you handle RPG style character advancement?
From what I have seen RPG lite systems set in a restricted environment such as the System/Bioshock series have relied on very accelerated character development through cybermodules/plasmids, both being a "magical" speed character advancement speed. In an even slightly more realistic setting like Shadowrun this sort of advancement would be difficult to pull off unless we resort to "super cybernetic upgrades the AI was secretly developing", but that still leaves non-cyber users out of the loop.
To the forum at large, is it possible to incorporate RPG character advancement in an enclosed environment, especially one in which real time and game world time are roughly equal?