That's like half of their games.
NWN has the best interface of all Bioware games. I know, it has a MMO-like hotkey bar, but the wheel thingy is intuitive, easy to use, and the inventory is very comfortable. Sadly, the main campaigns are really meh; the OC is atrociously bland. Not bad, just bland, which is worse than being bad.
IE is good for party based games, but managing stuff like Bags of Holding and other containers can be a bit tiresome, especially by mid-late BG2, because you have tons of shit. Luckly ToB introduced ammo containers.
Dragon Age's interface is comfy as well but it's just NWN 2.0, and the story, while better than NWN, is still ASoIaF-fanfic tier.
Mass Effect 1's inventory is absolute garbage though. It's confusing, you don't get immediate access to the weapons' upgrades, and you have to micromanage third person combat without isometric camera options. It's as bad as it sounds. ME2 at least made combat more "dynamic", which meant corridor popamole. However 2 had this "brilliant" thing which makes you download all the story related DLCs if you want to experience the whole game.
In short: avoid everything after KOTOR with the exception of DA:O which had a zoomed-out, kinda-isometric camera option.