Yeah, Vicissitude 4 gives access to the Horrid Form (+3 to all Physical attributes, all Social ones go to 0), but at that point you're just evening the playing field.Tzimisce Elders also could, so I would assume those of the other Clans would also find their ways.Only a heavily geared mage, mummy or demon can stand up to even a half-decent werewolf.
Come to think of it, a well-tuned changeling might also be able to defeat a Garou, but that's less about fisticuffs and more about yeeting that motherfucker into space.