games that feature the/a plague/a pandemic that I know of:
Deus Ex - Gray Death (cyberpunk stealth with RPG elements)
Neverwinter Nights - Wailing Death (Bioware RPG)
Greedfall - Malichor (action-RPG & cutscene simulator)
Dishonored - Rat Plague (steampunk stealth)
A Plague Tale - haven't played it, but I know it's the central theme (fantasy stealth)
Patrician & Anno series - plague (trading management & city builder)
Penumbra: Black Plague - haven't played it yet (horror adventure/stealth)
Entomorph: Plague of the Darkfall - a "plague" that turns people into insects ... (action game/RPG)
what else is there?
Deus Ex - Gray Death (cyberpunk stealth with RPG elements)
Neverwinter Nights - Wailing Death (Bioware RPG)
Greedfall - Malichor (action-RPG & cutscene simulator)
Dishonored - Rat Plague (steampunk stealth)
A Plague Tale - haven't played it, but I know it's the central theme (fantasy stealth)
Patrician & Anno series - plague (trading management & city builder)
Penumbra: Black Plague - haven't played it yet (horror adventure/stealth)
Entomorph: Plague of the Darkfall - a "plague" that turns people into insects ... (action game/RPG)
what else is there?