Item damage/destruction is a great idea.
Especially if there are hidden files/file sections that count reloads and assign xp penalties if there are more than 3 in a 24 hour period.
Perhaps allow 3 more that are "Save and Quit".
Or only allow the 3 "save and quit" in a 24 hour period.
The game should also keep track of item destruction by setting a rarity/value variable in the hidden file/section. If a reload occurs within a randomly determined 15-200 seconds after a high value item is destroyed, the xp penalties are increased, perhaps by a factor based on the value of the item or items.
Together with food, water, pain, and fatigue meters, the item destruction reload penalty will greatly enhance the gaming experience.
Oh, and bodies of fallen comrades should be full weight and take up a lot of Tetris inventory space.
I would allow rotating items in the inventory to help them fit.
Also, there should be aging and scars and magical healing/ressurection should cause pain and fatigue and perhaps permanent and/or semi-permanent stat loss.
Ressurection should cause some xp penalty, but the xp should also be regained at a faster rate because the character gets flashes of insight/unblocks chunks of lost memory.
Oh, and sleep requirements, including setting up guards and assigning watch rotations. Perhaps have every campsite be like a little fort, with positioning of guards, traps, 8-hour+ duration summons, etc. being a sort of minigame.
"Fantasy Adventure Simulator"
You know you want it!