Dragon Age Origins and Mass Effect 2 were the apex of Bioware. They were also the last "authentic" Bioware games. Others may not feel that way but both were in development before EA took over and had consolidated their power.
As far as profit goes, it was Maybe Mass Effect 2 and 3. Dragon Age: Origins probably didn't sell even as good as ME3. Simply, because there are no guns in it and the Call of Duty/Medal of Honor zombies can't be satisfied, if they can't shoot bullets in a game.
ME 3- despite causing some outrage with its plot and playing just like ME2 was a financial success. People bought it because of ME2 and Shepard and people are curious about gay sex and guys who like pretending to be a woman.
Their advertising strategy goes (guessing from just their history) as
1. Make a good selling game (see Mass Effect 2 or D.A.:O)
2. Add some DLC, which can be made within a week or 2. - rake in fanboy money.
3. Follow up with sequel, which can be completed under a year. Even if it's the biggest shit pile of all shit, their branding and rep from the previous title will generate income from the braindead fanboys.
..................tic-toc-tic-toc......
4. Fanboys forgot about how shitty it was before, and there is a new generation of gamers out there, knowing nothing about companies, beside what the gaming sites BS about them.
5. Work on a new title - which takes years and millions of dollars - make sure it's a "game of the year". This project can be started, right after the shitty sequel released (see point 3.)
6. It's time for a new shitty cheap sequel. There is a big group of newly recruited fanboys, who will buy whatever mess they dare to shove out as long as the title and the game resembles the previous "success" or "game of the year" title from 3-4 years ago.
Rinse....repeat...rinse ..repeat... Cha ching!
Just as a reminder, these are not good games at all. They are money makers, cheap shallow trash. McDonalds RPGs. The problem is, that people forgot what a good game is, so if a game come along, that semi-tries to be intelligent, half of the gaming community thinks it's a goddamn miracle, while the other half calls it "hard" , because it doesn't play like farmville on Facebook.